Analgesic, Anti-inflammatory and Antidiabetic Properties of Harpagophytum Procumbens Dc

In an attempt to scientifically appraise the ‘healing po Harpagophytum procumbens DC [family: Pedaliaceae], efficacy and safety of the medicinal plant product, we hav effects of the plant’s secondary root aqueous extract (HP rabbit isolated gastro-intestinal smooth muscle preparation animal study indicate that relatively low to high doses secondary root aqueous extract (HPE, 10–1000 μg/ml) significant (P<0.05–0.001), atropine-sensitive contrac oesophagus and guinea-pig isolated ileum. Relatively mo the plant’s extract (HPE, 200–1000 μg/ml) usually in biphasic responses in the rabbit isolated duodenum. Rela plant’s extract (HPE, 10–100 μg/ml) usually produced an significant (P>0.05) increase in the amplitude of the sp pendular contractions of the rabbit duodenal muscle pr relatively moderate to high concentrations of the plant’s always produced initial slight, significant (P<0.05–0.0 contractile amplitudes of the rabbit isolated duodenum. Th contractile amplitudes of the isolated rabbit duodenum c high concentrations of the plant’s extract (HPE, 200–1000 Afr. J. Traditional, omplementary and lternative Medicines africanethnomedicines.ne PROCUMBENS DC ACT ON ISOLATED CK, GUINEA-PIG d John A. O. Ojewole , University of KwaZulu-Natal, outh Africa kzn.ac.za wers’ and medicinal value of and throw some light on the e examined the pharmacological E) on the chick, guinea-pig and s. The results of this laboratory of Harpagophytum procumbens provoked concentration-related, tions of the chick isolated derate to high concentrations of duced concentration-dependent, tively low concentrations of the initial slight, transient and nonontaneous, myogenic, rhythmic, eparations. On the other hand, extract (HPE, 200–1000 μg/ml) 1) reductions (inhibitions) of e initial slight depressions of the aused by relatively moderate to μg/ml) were always followed by